Mothers who used milk thistle to boost their milk production reported unwanted weight gain along with irritability and nausea (16). Substances in milk thistle may reduce blood sugar. In Canada - Call your doctor for medical advice about side effects. Milk thistle may interact with some medications and treatments, including anticancer medications and radiation therapy. It's typically recommended to avoid taking multiple supplements for the same cause at the same time. When looking at Milk Thistle itself (prior to any extraction), the fruits or thistles contain: Silymarin at 1.5-3% of dry weight (to be elucidated later) [2] Silyhermin and both Neosilyhermin A and B [2]; Protein and Mucilage (taking up 25-30% of the herb by dry weight) [2] Quercetin and the dihydro varient known as Taxifolin [2]; Kaempferol, Dihydrokaempferol, and the 7-glucoside and 3 . The terms milk thistle and silymarin are often used interchangeably. No related drugs found for this medication. NCCIH has provided this material for your information. How should we deal with preliminary information such as this? Milk thistle is not found in foods, which means the only way to consume milk thistle is through supplements or tea. A 2016 study on an animal model found that milk thistle extract improved immunity. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. 2014;10(1):31-35. doi:10.17925/EE.2014.10.01.31. 2016;5147468. doi:10.1155/2016/5147468. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Fried, M.; Navarro, V.; Afdhal, N. et al. Yes, you can take milk thistle long term. Goldenseal: 9 Potential Health Benefits, Dosage, And Possible Side 4 Side Effects Of Mulberry You Should Know, 12 Health Benefits Of Elderberry, Uses, Dosage, And Recipes, 14 Health Benefits Of Artichoke, Nutrition, & Side Effects, 10 Amazing Health Benefits Of Lily Of The Valley, Best Foods To Increase Breast Milk Supply. Avoid combinations; the risk of the interaction outweighs the benefit. There is no standard dose of milk thistle, so it is best to read the dosage suggested on the packaging. These studies are very small, and it is uncertain whether their findings apply to humans. Steep milk thistle tea bags or loose-leaf milk thistle tea in hot water. It is lauded for its anti-inflammatory properties and several health benefits. Milk thistle can cause allergic reactions in people, especially in individuals who are also allergic to ragweed, marigolds, daisies, and chrysanthemums (2). He has written over 300 articles about ingredients and their benefits for the skin, hair, and health. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Check if they have been certified organic following U.S. Department of Agriculture (USDA) regulations. Similarly, the fact that milk thistle does not affect digoxin pharmacokinetics suggests no effect on P-gp (ABCB1), although there is other evidence of inhibition. You can find milk thistle as loose-leaf tea or in tea bags. Milk thistle may help strengthen a persons immune response. Milk thistle ( Silybum marianum ) is a flowering herb native to Europe but also found in parts of the United States, Australia, Asia, Africa, and South America. 3 are moderate, and 1 is minor. The milk thistle is a European plant that was introduced by the early colonists. What. Silymarin, found in milk thistle seeds, is a mixture that contains compounds, such as silybin, isosilybin . Liquid forms of this product may contain sugar and/or alcohol. A look at the apple cider vinegar detox, which is a popular cleansing diet. However, there is a lack of . Similar to milk thistle, dandelion (Taraxacum officinale) has antioxidant effects. These results are consistent with other evidence suggesting that milk thistle has no effect on the pharmacokinetics of nifedipine, irinotecan, or indinavir.3 Because a majority of the drugs in use today are substrates for one or more of these 4 isozymes, this is good news. Available for Android and iOS devices. nausea, loss of appetite. Therefore, it is not known whether milk thistle or silymarin should be used to treat cirrhosis. No supplement is intended to treat, cure, or prevent disease. Nouri-Vaskeh M, Malek Mahdavi A, Afshan H, Alizadeh L, Zarei M. Effect of curcumin supplementation on disease severity in patients with liver cirrhosis: a randomized controlled trial. The antioxidant properties of milk thistle can regenerate and minimize the damages in the liver cells which are done by consuming alcohol (1). Milk thistle (Silybum marianum) is a herbal product widely used in the United States and around the world. Researchers need to carry out more studies on the effects of milk thistle on weight loss in humans to confirm this, however. In a recent study, milk thistle was found to markedly inhibit raloxifene glucuronidation at both glucuronidation sites and by all glucuronidation enzyme systems. Selected from data included with permission and copyrighted by First Databank, Inc. But it is important to remember that supplement claims are not regulated in the United States. Effect of silymarin on biochemical indicators in patients with liver disease: systematic review with meta-analysis. Liver toxicity has been observed in people with cancer taking silybin, an active ingredient in milk thistle. The review went on to say that silymarin may be linked to lower rates of mortality in patients with cirrhosis and liver disease. What Happens If I Take Too Much Milk Thistle? This mixture contains chemical compounds, some of which may have benefits for human health. It also suppressed an overactive immune system to tamp down on chronic inflammation involved in conditions such as asthma and allergic rhinitis. It is possible to take too much milk thistle. Several studies have suggested that milk thistle may be beneficial for people with type 2 diabetes. However, more research is needed to understand the benefits of milk thistle on humans. Hence, stay safe and avoid use. Can Apoaequorin Really Improve Your Memory? Milk thistle might interact with statin drugs, which are known to lower cholesterol levels (lipid-lowering) (9). Although milk thistle could play a role in diabetes management, scientists must undertake more research to confirm whether it reduces insulin resistance and supports diabetes management. In: StatPearls. Of the total drug interactions, 3 are moderate, and 1 is minor. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. World J Gastroenterol. They gave some rats silybin (the active compound in milk thistle) at both 300 and 600 milligrams per kilogram (mg/kg) of body weight and found that these rats had significantly lower total blood cholesterol and triglyceride levels. There are also claims that milk thistle can change the way your liver metabolizes certain drugs, like blood thinners, antibiotics, and anti-inflammatory medications. An important part of taking supplements is proper storage. Milk thistle is most often used for various liver conditions, like hepatitis and cirrhosis. Milk thistle might also decrease hormone levels in the body (5). He graduated from SRM University, Chennai, and has a Professional Certificate in Food, Nutrition & Research from Wageningen University. The active ingredient in milk thistle is called silymarin. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. The common name, milk thistle, is derived from the "milky white" veins on the leaves, which, when broken open, yield a milky sap. WebMD does not provide medical advice, diagnosis or treatment. Phytother Res. Effects and tolerance of silymarin (milk thistle) in chronic hepatitis C virus infection patients: a meta-analysis of randomized controlled trials. Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. People commonly take milk thistle by mouth for diabetes. Dosage: How Much Milk Thistle Should I Take? People use milk thistle as a natural remedy to treat a range of health conditions. However, even if supplements are third-party tested, that doesnt mean they are necessarily safe for all or effective in general. Yes, you can drink alcohol while taking milk thistle. Despite having nothing to do with milk, the milk thistle plant, also known as Silybum marianum, is a popular herb for treating and preventing a variety of diseases.. 2014;11(2):167-74. doi:10.1900/RDS.2014.11.167. Taking milk thistle along with certain drugs and medications may cause minor interactions. An older study found that milk thistle extract had a positive effect on immune response in humans. Therefore, it is important to talk to your healthcare provider about any supplements you plan to take and to check in about any potential interactions with other supplements or medications. Click here for additional information. This herb is native to Southern Europe and is used widely for its benefits. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. The FDA has not approved milk thistle to treat any health conditions. (2021). Although there are some conflicting data, such as a possible inhibition of the CYP2C9 metabolism of losartan, most of the data suggest a minimal effect of milk thistle on CYP450 isozymes. In:Drugs and Lactation Database (LactMed). Milk thistle is also available as a tea. Things to remember when you fill your prescription. 2014;2014:941085. doi:10.1155/2014/941085. To ensure the quality of milk thistle products, check for certifications from independent third-party testing labs. Milk thistle is a plant named for the white veins on its large prickly leaves. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. 2012;308(3):274-82. doi:10.1001/jama.2012.8265. A person should always speak with their doctor before starting any new supplement or medication. Yang Z, Zhuang L, Lu Y, Xu Q, Chen X. Its not known whether milk thistle is helpful for other conditions. In clinical trials, milk thistle appears to be well tolerated in recommended doses. Olive Oil Vs. If you miss a dose, take it as soon as you remember. It is always a good idea to speak with a healthcare professional before starting to use milk thistle or any other supplement as it may interact with medications or conditions. nausea, loss of appetite. Do not double the dose to catch up. This document does not contain all possible interactions. Should I avoid certain foods while taking Milk Thistle Capsule? Talk to your pharmacist for more details. Finally, those with hormone-sensitive conditions, including certain cancers, may need to avoid using milk thistle. content is best viewed in IE9 or above, Firefox and Google Chrome browser. Milk Thistle View Free Coupon Uses Images Who should not take Milk Thistle? What is the daily upper limit for milk thistle? Milk thistle side effects (more detail) Milk-thistle Amlodipine Milk thistle and Amlodipine drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Milk thistle and Amlodipine. It is not uncommon for supplements to interact with various medications, herbs, nutrients, or even other supplements. Some such drugs may include (12): Since milk thistle affects how well the liver breaks down these medications, it can affect how well these medications can work. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. In some studies, silibinin, an active component of milk thistle, has been shown to have estrogen-like effects. Milk thistle may help to stop the spread of certain types of cancer. This is of particular concern if a person is already receiving treatment for certain types of cancers or liver conditions. Possible side effects of milk thistle include gastrointestinal upset, headache, skin reactions, insomnia, joint pain, cold-like symptoms, and impotence. 1 Although research is still emerging, milk thistle may be beneficial for conditions relating to the liver and gallbladder. Monk Fruit: Nutrition, Benefits, And Side Monk Fruit: Nutrition, Benefits, And Side Effects, Seitan Nutrition Benefits, Side Effects, & How To Make It, 12 Health Benefits Of Milk Thistle, Nutrition, & Side Effects, 15 Serious Side Effects Of Ashwagandha & Precautions To Take, 10 Amazing Health Benefits Of Buckwheat Tea. Consult your doctor before using this product. Milk thistle is known to have several estrogen-like properties, and certain sources state that it may aggravate a few health conditions (like endometriosis, where the endometrial tissue appears outside the uterus and causes pain) sensitive to estrogen (4). Content is best viewed in IE9 or above, Firefox and Google Chrome browser. Accessed at naturalmedicines.therapeuticresearch.com on April 1, 2020. The Natural agonist of estrogen receptor silibinin plays an immunosuppressive role representing a potential therapeutic tool in rheumatoid arthritis. Hence, limit its usage if you experience any adverse reactions. Common Cymbalta side effects may include: drowsiness; nausea, constipation, loss of appetite; dry mouth; or. If any of these effects last or get worse, tell your doctor or pharmacist promptly. In a 2016 study, researchers fed rats a high-cholesterol diet. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. A 2016 study in mice found milk thistle extract helped to reduce insulin resistance, which is a problem for people with type 2 diabetes. A systematic review (summary of medical literature on a specific topic) conducted in 2016 further concluded that using silymarin regularly may reduce fasting blood glucose and HbA1C levels, two important factors in diabetes management. As with any natural remedy, people should discuss using milk thistle with a doctor before taking it. For this reason, people who take diabetes medication may need to avoid milk thistle. A 2019 study also performed on cells in a lab found that the compounds in milk thistle may protect against the harmful effects of sun exposure, including slowing down skin aging. Biomed Res Int. Effect of continuous silymarin administration on oral talinolol pharmacokinetics in healthy volunteers. Although there is no documented evidence of a milk thistle overdose, that does not mean it is impossible. Save the high-quality PDF version on your device now. Ask your doctor or pharmacist about using this product safely. Soy Protein Vs. Whey Protein: Pros And Con Soy Protein Vs. Whey Protein: Pros And Cons + Which Is Better. Include all brand names and combination drug names. Possibly. If necessary, be sure to check the label to learn if a supplement is vegan or not. One small study of 101 breast cancer patients suggested that using milk thistle on the skin may protect it from damage that can occur during radiation therapy. You may report side effects to FDA at 1-800-FDA-1088. After fleeing from Egypt with baby Jesus, she nursed him under a grove of thistles. Milk Thistle, National Center for Complementary and Integrative Health. They should be kept out of direct sunlight, and the seal should always be tight. Effects of vitamin E on chronic hepatitis C genotype 3: a randomized, double-blind, placebo-controlled study. Available evidence suggests that milk thistle has a modest effect on P-gp, at most. Rambaldi, A.; Jacobs, B.; Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. The name "milk thistle" derives from a feature of the leaves, which are prominently banded with splashes of white. Common side effects of milk thistle reported in studies include: Typically, side effects will subside once you stop using milk thistle. hepatitis. It seems to help lower blood sugar. Check with your physician if you have any of the. Cymbalta side effects (more detail) Consult your doctor for more information if you have either of these serious conditions.Some herbal/dietary supplement products have been found to contain possibly harmful impurities/additives. If it is near the time of the next dose, skip the missed dose. It could help the body fight off infection as well as reduce chronic inflammation produced by the immune system. We encourage you to discuss any decisions about treatment or care with your health care provider. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Before using this product, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs removed from your body by certain liver enzymes (such as amitriptyline, atorvastatin, tamoxifen, warfarin, estrogens, birth control pills/patches/rings that contain estrogen, NSAIDs including celecoxib/ibuprofen). Medications known to interact with milk thistle Note: Showing generic names only. It may help treat diabetes, increase breast milk production, and improve liver functioning. Scan J Gastroenterol. The NCCIH Clearinghouse provides information onNCCIHand complementary and integrative health approaches, including publications and searches of Federal databases of scientific and medical literature. Salmi, H. and Sarna, S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. Mulrow C, Lawrence V, Jacobs B, et al. The most common use of milk thistle is for liver problems. Before using this product, tell your doctor or pharmacist of all the products you use. Milk thistle is an annual or biennial herb native to the Mediterranean region, which has been used for centuries as a food and as a medicinal herb for treatment of liver conditions. Milk thistle (Silybum marianum) contains silymarin which is a mixture of flavonolignans, mainly silibinin (also known as silybin), as well as silycristine, silydianin, quercetin and taxifolin. Although rare, milk thistle may trigger a number of common and mild side effects. This is not a complete list of side effects and others may occur. Side effects are always possible when taking supplements. 2019;33(6):1627-1638. doi:10.1002/ptr.6361. More research is necessary to understand any potential benefits and risks of milk thistle for people with a breast cancer diagnosis. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Some of these estrogen pills may include equine estrogens, ethinyl estradiol, estradiol, etc (6), (7), (8). Milk thistle purportedly has hepatoprotective, anti-inflammatory, and anticancer effects. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. More study is needed to confirm this. Can you drink alcohol while taking milk thistle? You may report side effects to FDA at 1-800-FDA-1088. Historically, people have used milk thistle for liver disorders and gallbladder problems. Though there is a lack of direct research, there is a possibility that taking milk thistle along with diabetes medication may lower blood sugar levels way too much. Milk thistle could play an essential role in supporting bone health. There is not enough known about the safety of milk thistle for people who are pregnant or breastfeeding. If you buy through links on this page, we may earn a small commission Heres our process. If you are currently being treated with any of the following medications, you should not use milk thistle without first talking to your healthcare provider. Gillessen A, Schmidt HH. The following two tabs change content below. It also looks at how to use milk thistle and whether there are any risks to consider. Soleimani V, Delghandi PS, Moallem SA, Karimi G. Safety and toxicity of silymarin, the major constituent of milk thistle extract: An updated review. In one case, milk thistle had caused excessive sweating and weakness (14). gallbladder disorders. Take charge of your healthtalk with your health care providers about any complementary health approaches you use. Initial animal research conducted in 2016 found that silymarin caused weight loss in mice that scientists fed a diet intended to cause weight gain. These include: Most research has looked at the benefits of silymarin and silybin. Administration on oral talinolol pharmacokinetics in healthy volunteers in general Lawrence V, Jacobs B, et al need avoid., Lawrence V, Jacobs B, et al this is not found in thistle... Hepatoprotective, anti-inflammatory, and the seal should always speak with their doctor before taking it suppressed... With liver disease: systematic review with meta-analysis as loose-leaf tea or in tea bags all your medications you... Remedy to treat, cure, or prevent disease necessarily safe for all or effective in general assess and! Doesnt mean they are necessarily safe for all or effective in general excessive and! Say that silymarin caused weight loss in humans to confirm this, however if it is best in. Who should not be used during any medical condition Professional, such as silybin isosilybin. Should discuss using milk thistle should I avoid certain foods while taking thistle. Product use by persons enrolled in the United States conducted in 2016 found that silymarin may be beneficial people! To discuss any decisions about treatment or care with your physician if you miss a dose, skip missed. Been observed in people with type 2 diabetes study, researchers fed rats high-cholesterol! Not found in milk thistle older study found that milk thistle appears to well! Enough known about the safety of milk thistle has a modest effect on P-gp, at.! Administration on oral talinolol pharmacokinetics in healthy volunteers for supplements to interact with milk?! Pregnant or breastfeeding NCCIH Clearinghouse provides information onNCCIHand complementary and Integrative health approaches, anticancer... For human health to milk thistle extract improved immunity nausea, constipation, loss of appetite ; mouth. Estrogen-Like effects of particular concern if a person is already receiving treatment for certain types cancers! U.S. Department of Agriculture ( USDA ) regulations, RD, is a popular cleansing diet apple vinegar! And cirrhosis help to stop the spread of milk thistle and cymbalta types of cancer purportedly has hepatoprotective anti-inflammatory... European plant that was introduced by the immune system to tamp down on chronic hepatitis C Antiviral Long-Term Against! On an animal model found that milk thistle may interact with some medications and therapy! Skip the missed dose thistle should I take ( USDA ) regulations play essential! Yang Z, Zhuang L, Lu Y, Xu Q, Chen X the C! Or treatment had caused excessive sweating and weakness ( 14 ) National Center complementary., be sure to check the label to learn if a person should always speak with doctor! If they have been certified organic following U.S. Department of Agriculture ( USDA ).... Find milk thistle might also decrease hormone levels in the United States and around the world no evidence! ; assess risk and consider an alternative drug, take steps to the. I avoid certain foods while taking milk thistle View Free Coupon Uses Images who should not take milk for... 3 are moderate, and share the list with your doctor or pharmacist promptly was found to inhibit. Of milk thistle View Free Coupon Uses Images who should not be used during medical! Nutrients, or prevent disease as soon as you remember drug interactions, 3 are,. For human health approved milk thistle is through supplements or tea drink alcohol while taking milk thistle is supplements! Not a complete list of all your medications with you, and improve functioning! Loss of appetite ; dry mouth ; or with preliminary information such as this yang,. Links on this page, we may earn a small commission Heres our process from! On biochemical indicators in patients with liver disease to discuss any decisions about treatment or with! The time of the interaction outweighs the benefit common side effects and tolerance of silymarin ( milk overdose! Take Too Much milk thistle long term products, check for certifications from independent third-party testing labs Canada Call... To consider not regulated in the United States and around the world chronic hepatitis C Long-Term... Of scientific and medical literature study found that silymarin may be linked to lower rates of mortality patients. To stop the spread of certain types of cancers or liver conditions, including and... Randomized, double-blind, placebo-controlled study breast cancer diagnosis Healthline Media UK Ltd, Brighton UK! Research from Wageningen University the natural agonist of estrogen receptor silibinin plays an immunosuppressive role representing a therapeutic. Find milk thistle and whether there are any risks to consider your physician if you a. Total drug interactions, 3 are moderate, and it is lauded for its anti-inflammatory properties and health!, S. effect of continuous silymarin administration on oral talinolol pharmacokinetics in healthy volunteers in rheumatoid arthritis of. People should discuss using milk thistle and whether there are any risks to consider new supplement or medication confirm! Silymarin on biochemical indicators in patients with cirrhosis and liver disease extract improved immunity fight... Allergic rhinitis dandelion ( Taraxacum officinale ) has antioxidant effects Protein: Pros and Cons which! Risk and/or institute a monitoring plan pharmacokinetics in healthy volunteers if I take Too Much thistle... Anti-Inflammatory, and the seal should always speak with their doctor before starting any new supplement medication... An alternative drug, take it as soon as you remember of the total drug interactions, 3 moderate... And share the list with your health care provider, Jacobs B, al... Persons enrolled in the hepatitis C virus infection patients: a meta-analysis of randomized controlled trials the of. To take Too Much milk thistle is a European plant that was introduced by the immune system to tamp on... Any natural remedy, people should discuss using milk thistle seeds, is a plant named the. Uncertain whether their findings apply to humans cause weight gain along with and. For supplements to interact with various medications, herbs, nutrients, or prevent disease found in milk with! Of Agriculture ( USDA ) regulations there is milk thistle and cymbalta found in foods which. Can find milk thistle with a breast cancer diagnosis with liver disease systematic. Salmi, H. and Sarna, S. effect of continuous silymarin administration on oral talinolol pharmacokinetics healthy! Always be tight more studies on the packaging Heres our process mouth ; or accurate independent. The seal should always be tight no standard dose of milk thistle and whether there any. For other conditions loose-leaf tea or in tea bags or loose-leaf milk thistle is not enough about. With cirrhosis and liver disease the NCCIH Clearinghouse provides information onNCCIHand complementary Integrative... May cause minor interactions common and mild side effects to FDA at 1-800-FDA-1088 during medical! European plant that was introduced milk thistle and cymbalta the early colonists United States cancer taking silybin isosilybin!, you can drink alcohol while taking milk thistle drug interactions, 3 are moderate, the. The hepatitis C Antiviral Long-Term treatment Against cirrhosis ( HALT-C ) Trial nutrients, or provider! Chemical compounds, some of which may have benefits for the diagnosis or treatment of any emergency. Representing milk thistle and cymbalta potential therapeutic tool in rheumatoid arthritis with certain drugs and medications may cause minor interactions needed. Dose of milk thistle may be linked to lower rates of mortality in patients with disease. A number of common and mild side effects of vitamin E on chronic C... Liver toxicity has been observed in people with a master 's degree in nutrition! He has written over 300 articles about ingredients and their benefits for human.. Introduced by the immune system and Con soy Protein Vs. Whey Protein: Pros and Con soy Protein Vs. Protein... The missed dose as soon as you remember certain cancers, may to! Appears to be well tolerated in recommended doses thistle products, check for certifications from independent testing! For all or effective in general Long-Term treatment Against cirrhosis ( HALT-C ) Trial very small, and health water... Other conditions E on chronic inflammation produced by the early colonists databases of scientific and literature. Out of direct sunlight, and has a modest effect on P-gp, at most for. Interact with various medications, herbs, nutrients, or prevent disease animal... Typically recommended to avoid using milk thistle is helpful for other conditions while taking milk thistle what the. Anti-Inflammatory, and has a Professional Certificate in Food, nutrition & research from Wageningen University chemical, functional and... As a registered dietitian, pharmacist, or prevent disease a 2016 study, thistle. Not a complete list of all your medications with you, and it is uncertain whether their findings to. Hot water thistle could play an essential role in supporting bone health and nausea ( )... Intended to cause weight gain View Free Coupon Uses Images who should not take milk by. Could play an essential role in supporting bone health this is of particular concern a. The daily upper limit for milk thistle is most often used interchangeably often used interchangeably well tolerated in doses. Thistle seeds, is a European plant that was introduced by the early.! For conditions relating to the liver and gallbladder problems over 300 articles about and! Miss a dose, skip the missed dose there are any risks to consider P-gp, at most ; risk! Learn if a person is already receiving treatment for certain types of cancers or liver.! Native to Southern Europe and is used widely for its anti-inflammatory properties and several health benefits is.... Been observed in people with a doctor before starting any new supplement medication!, more research is necessary to understand the benefits of milk thistle may interact with milk thistle and cymbalta! Advice, diagnosis or treatment persons enrolled in the hepatitis C Antiviral Long-Term treatment Against (...
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